Weight-Loss Drug Zepbound Cost Drops To $299 A Month After Trump Deal

Topline

Eli Lilly on Monday lowered the cost of Zepbound after the pharmaceutical giant and Ozempic maker Novo Nordisk announced a deal with the Trump administration to slash the prices of the popular weight-loss drugs.

Key Facts

The out-of-pocket monthly price for the lowest single-dose vial of Zepbound is now $299 when purchased through Eli Lilly’s platform LillyDirect, a 14% decrease from $349, while the 5-milligram dose was cut to $399, a roughly 20% cut from $499, Eli Lilly announced.

Prices for the 7.5 through 15 milligram doses were reduced to $449 from $499.

Novo Nordisk announced last month the out-of-pocket monthly price of Ozempic and Wegovy would be lowered to $349 from $499, and that the two lowest doses of either drug would be available for $199 per month for the first two months.

Eli Lilly’s shares fell nearly 1% in premarket trading after the announcement, while Novo Nordisk’s stock traded down more than 1.7%.

Big Number

$1,086. That’s the monthly cost of Zepbound before any discounts or rebates, according to Eli Lilly. The list price for Ozempic is just over $997 per month.

Source: https://www.forbes.com/sites/tylerroush/2025/12/01/eli-lilly-lowers-weight-loss-drug-zepbound-prices-after-trump-deal/