Semler Scientific Quietly Builds One of the Top Bitcoin Treasuries

• Semler Scientific now ranks as the fourth-largest corporate Bitcoin holder in the United States.
• The company used equity funding to expand its long-term Bitcoin treasury strategy.

US medical device company Semler Scientific has solidified its position as one of the largest corporate institutions with Bitcoin holdings in the US.

Semler Scientific Quietly Climbs Into America’s Top Bitcoin Treasury List

The company has purchased an additional 167 BTC worth $16.2 million. With this latest accumulation, their total Bitcoin reserves have reached 3,634 BTC.

When multiplied by the current price—around $94,000 per BTC—the figure exceeds $340 million. Just imagine if all those BTC were arranged into physical coins and stacked up… it could be a monument, not just a collection of coins.

💥BREAKING

SEMLER SCIENTIFIC $SMLR BUYS 167 $BTC FOR $16.2M

NOW HOLDS 3,634 BITCOIN, BECOMING 4TH LARGEST U.S. BITCOIN TREASURY! pic.twitter.com/UFVcPSxHgl

— DustyBC Crypto (@TheDustyBC) May 5, 2025

What has raised many eyebrows is their current position: Semler officially sits as the fourth-largest Bitcoin holding company in the US, only behind MicroStrategy, Tesla, and Block. But wait, interestingly, this purchase is not the result of a lucky break.

The fresh funds came from a common stock offering worth almost $40 million that they conducted last April. So this is indeed a well-thought-out and well-funded decision—not just a trend-following one.

Bitcoin Is Becoming the Corporate Favorite Asset

Semler’s move doesn’t seem to be the only one. On the other hand, Rumble—a video platform that competes with YouTube—is also reported to have purchased 188 BTC. CNF reported that this move is part of their long-term financial strategy that is increasingly leaning towards digital assets.

Increasingly, it seems that Bitcoin is no longer just a matter for nerds or speculators, but has become something that many big players are taking seriously.

Furthermore, there is interesting news from the SPAC world. Cantor Equity Partners (CEP) shares have soared 462% due to a merger with 21 Capital, a crypto company backed by big names like Tether, Bitfinex, and SoftBank.

What’s exciting is that 21 Capital has plans to acquire around 42,000 BTC, making it a strong candidate to become one of the new “giants” among global Bitcoin holding companies. If so, they could even overtake MicroStrategy in the near future.

Besides that, in April, GameStop, a gaming retailer that previously went viral due to the “meme stock” phenomenon, announced the allocation of $1.5 billion from the company’s cash for a secret project called Project Rocket.

This project reportedly has a big mission: entering the world of Bitcoin. Although there has been no official purchase, the intention is enough to make investors start speculating on the direction of GameStop’s future.

However, all of these movements cannot be separated from one main trigger: the approval of the Bitcoin ETF that occurred 15 months ago. According to a report by EY and Capriole Investments, after the ETF was approved, it became easier for large companies to enter the crypto space.

Not only because the infrastructure is ready, but also because there is a higher level of trust from institutional investors. Bitcoin’s dominance itself has now reached 64% of the total crypto market, the highest level since 2021. That means that the focus of the big players is indeed returning to BTC—not to altcoins or meme tokens.

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