Drake London, Josh Jacobs And More

Week 11 of the 2025 NFL season was brutal from an injury perspective. Multiple starting quarterbacks and running backs left their respective games early and did not return.

Many of them appear to have dodged the worst-case scenarios, but that isn’t the case for all of them. The Atlanta Falcons will likely have a new quarterback under center for the rest of the season, while the Tennessee Titans’ receiving corps took a major hit as well.

Let’s walk through all of the major injury news that fantasy football managers need to know heading into Week 12.

Notable Injuries:

1. Drake London, Atlanta Falcons WR (knee)

Not only did the Falcons potentially lose starting quarterback Michael Penix Jr. for the season due to a knee injury (more on that later), but star wide receiver Drake London also suffered a knee injury that has him week-to-week. Head coach Raheem Morris told reporters that he’s dealing with a PCL issue, according to ESPN’s Marc Raimondi.

London has been the focal point of the Falcons’ passing game this year. He leads the team in receptions (60), receiving yards (810) and receiving touchdowns (six). Running back Bijan Robinson is second on the team in all three categories.

With London sidelined, new starting quarterback Kirk Cousins figures to funnel most of his targets through Robinson, wide receiver Darnell Mooney and tight end Kyle Pitts. If Mooney is available on your league’s waiver wire, he’s worth a speculative pickup due to the volume he’s expected to receive in London’s absence.

2. Josh Jacobs, Green Bay Packers RB (knee)

Shortly after quarterback Jordan Love exited the Packers’ 27-20 win over the New York Giants with a shoulder injury, star running back Josh Jacobs left with a knee injury. Love later returned to the game, but Jacobs did not.

On Monday, head coach Matt LaFleur told reporters that Jacobs avoided any structural damage to the knee and just has a contusion. He said Jacobs “potentially” could suit up for Sunday’s game against the Minnesota Vikings, but it’s a matter of “more or less trying to get the swelling down.”

Emanuel Wilson took over as the Packers’ lead running back in Jacobs’ absence, finishing with 11 carries for 40 yards and a touchdown along with one reception for nine yards. He should be owned in every league in case Jacobs can’t suit up Sunday, although Jacobs’ managers should breathe a sigh of relief that they at least avoided a long-term catastrophe.

3. Jaylen Warren, Pittsburgh Steelers RB (ankle)

Jacobs wasn’t the only starting running back to exit a game early on Sunday. After rushing 10 times for 62 yards and catching two passes for six yards, Jaylen Warren left in the third quarter with an ankle injury. He did return for one snap, but then he was done for the day.

After the game, Warren told reporters that he “could have” returned, but removing him “was part of being smart.” On Tuesday, head coach Mike Tomlin told reporters that Warren will be limited in practice early in the week because of the injury, but he’s “optimistic” that Warren will be available on Sunday against the Chicago Bears.

In Warren’s absence, Kenneth Gainwell finished with nine carries for 24 yards along with a team-high seven receptions for 81 yards and two touchdowns. The Steelers’ current uncertainty at quarterback clouds Warren and Gainwell’s outlook heading into Week 12, but Gainwell should be owned in 100% of leagues in the wake of Warren’s injury.

4. Calvin Ridley, Tennessee Titans WR (leg)

There’s no mystery about Calvin Ridley’s rest-of-season outlook. He fractured his fibula on the Titans’ first offensive snap against the Houston Texans on Sunday, which is a season-ending injury that landed him on injured reserve Tuesday.

In Ridley’s absence Sunday, tight end Chig Okonkwo led the Titans with 56 receiving yards on three catches. Running back Tyjae Spears hauled a team-high five catches, albeit for only 31 yards. No one else on the team topped 30 receiving yards, as rookie quarterback Cam Ward finished with only 194 passing yards on the day.

Ward has finished with fewer than 200 passing yards in five of his 10 starts thus far, which limits the upside for any Titans pass-catcher. Fantasy managers in standard 10- or 12-team leagues would be better off completely ignoring the Titans for now.

5. Michael Penix Jr., Atlanta Falcons QB (knee)

Michael Penix Jr.’s season is likely over. The Falcons placed him on injured reserve Monday after he aggravated a bone bruise and knee sprain and “suffered some damage to his ACL in his left knee, which could necessitate a full reconstruction,” according to NFL Network’s Ian Rapoport and Tom Pelissero.

Veteran quarterback Kirk Cousins will be replacing Penix for at least the next four games, if not the rest of the season. During his lone start this year, he finished 21-of-31 for 173 yards, zero touchdowns and zero interceptions in a blowout 34-10 loss to the Miami Dolphins. London missed that game as well, so that may be a preview of what’s to come for the Falcons in the near future.

Pitts was the leading receiver against Miami with nine catches for 59 yards. The biggest red flag may be for Bijan Robinson managers, as he had only nine carries for 25 yards and three catches for 23 yards in Cousins’ lone start. That would be a precipitous fall from the RB1 ranks if it continues.

6. Aaron Rodgers, Pittsburgh Steelers QB (wrist)

Warren wasn’t the only key Pittsburgh Steelers offensive player who suffered an injury Sunday. Starting quarterback Aaron Rodgers suffered a fracture to his left (non-throwing) wrist, although it will not require surgery, according to head coach Mike Tomlin.

“Really, it’s just about bracing it and securing it for his comfort and safety, and then it’s about how functional he is,” Tomlin told reporters Tuesday. “We don’t have the answers to that, as we stand here today, but certainly I would imagine we will get some clarity as we push through the week.”

Backup quarterback Mason Rudolph competently managed the Steelers’ offense in Rodgers’ absence Sunday, albeit against the Cincinnati Bengals, who boast the NFL’s worst defense. The Steelers’ Week 12 opponent, the Chicago Bears, aren’t much better in that regard, so Warren and DK Metcalf might be able to stay afloat even if Rodgers does miss time.

Quick Hits:

1. Kimani Vidal, Los Angeles Chargers RB (thigh)

Vidal suffered a thigh injury early in the second quarter of the Chargers’ blowout loss to the Jacksonville Jaguars, although he did return on their final drive before halftime. He finished with only five carries for 13 yards and two catches for minus-one yards. The Chargers are on bye in Week 12, so we likely won’t get an update on him until next week.

2. Dillon Gabriel, Cleveland Browns QB (concussion)

Gabriel suffered a concussion in the Browns’ loss to the Baltimore Ravens, which led to Shedeur Sanders making his regular-season debut. However, Sanders finished 4-of-16 for 47 yards, zero touchdowns and one interception. Head coach Kevin Stefanski already said that Gabriel will reclaim the starting gig this week if he clears concussion protocol in time.

3. Chimere Dike, Tennessee Titans WR (chest)

As if losing Ridley wasn’t bad enough, the Titans also lost Chimere Dike to a chest injury that he suffered after muffing a punt shortly before halftime, per ESPN’s Turron Davenport. If he’s out for Week 12, Van Jefferson and Elic Ayomanor may be the last men standing in the Titans’ receiving corps.

4. Eddy Piñeiro, San Francisco 49ers K (hamstring)

Piñeiro suffered a Grade 1 hamstring strain in the third quarter of the Niners’ blowout win over the Arizona Cardinals on Sunday and could be out multiple weeks, according to Eric Branch of the San Francisco Chronicle. The Niners are set to work out kickers to replace him, so managers with Piñeiro on their roster need to be making alternative plans for Week 12.

5. Xavier Legette, Carolina Panthers WR (hip)

Legette injured his hip late in the Panthers’ overtime win against the Atlanta Falcons, but he told reporters Tuesday that he expects to play in their Week 12 game against the San Francisco 49ers on Monday. If that changes, Jalen Coker could be worth a one-week flier, as he finished with four catches for 52 yards against Atlanta.

6. Emari Demercado, Arizona Cardinals RB (ankle)

The Cardinals’ never-ending game of running back roulette continues, as Demercado suffered a high ankle sprain against the Niners and is “unlikely to play Sunday” against the Jacksonville Jaguars, per ESPN’s Adam Schefter. If the Cardinals don’t activate Trey Benson from IR this week, Bam Knight and Michael Carter project to split the backfield work for Arizona in Week 12.

Possible Returns

1. MarShawn Lloyd, Green Bay Packers RB (hamstring)

Packers head coach Matt LaFleur told reporters Monday that Marshawn Lloyd could be activated from injured reserve this week, although there’s no guarantee he’d be ready to make his season debut Sunday. If Josh Jacobs misses multiple weeks, though, Lloyd would be worth a speculative add, particularly for managers with an open IR spot.

2. Jayden Reed, Green Bay Packers WR (collarbone)

LaFleur said Jayden Reed also could be activated from IR this week. Reed caught three passes for 45 yards and a touchdown in the Packers’ season-opening win over the Detroit Lions before breaking his collarbone in Week 2 and going on IR. With tight end Tucker Kraft done for the year with a torn ACL, the Packers could use all of the pass-catching help they can get. Reed would also be worth a speculative add with that in mind.

3. Jaxson Dart, New York Giants QB (concussion)

On Monday, interim Giants head coach Mike Kafka didn’t give much of an update on Jaxson Dart, who missed the Giants’ loss to the Packers with a concussion. Even if he does return Sunday against the Lions, he might not be running quite as much as he did prior to the injury.

Source: https://www.forbes.com/sites/bryantoporek/2025/11/19/week-12-fantasy-football-injury-report-drake-london-josh-jacobs-and-more/