Polkadot’s flagship event brings together the leading figures of the Web3 ecosystem.
Buenos Aires, November 2025 – WebZero and Polkadot announce that Dr. Gavin Wood, founder of Polkadot and co-founder of Ethereum, will be the keynote speaker at sub0 Symbiosis and will kick off the event with the opening keynote address on November 14 at 11:00 AM (local time). In his first major public appearance since returning as CEO of Parity, Dr. Wood will headline the distinguished list of Web3 experts confirmed for this flagship conference, which will take place from November 14-16 at Bubble Studios, Buenos Aires.
Prior to his presentation, Dr. Wood reflected on the evolution of Polkadot and the future of the network: “Technical excellence remains the foundation of Polkadot, but now the priority is adoption and usability. As we enter this new era, Polkadot will become the ‘world supercomputer’ for the next generation of Web3.”
With a focus on development, the event will bring together developers, innovators and thought leaders for three days of keynote speeches, panels, interviews, workshops, a hackathon and the best energy of the Web3 ecosystem.
Confirmed speakers include: Jakub Panik (Co-Founder & CTO, Hydration ), Ed Hesse (Co-Founder & CEO, EnergyWeb ), Seun Lanlege (Co-Founder & CEO, Hyperbridge ), Amar Singh (Senior Rust Engineer, OpenZeppelin ), Paul Sparta (CEO, Vbrick ), Francesco Andreoli (DevRel, MetaMask ), Alberto Viera (DevRel Lead, Moonbeam ), Nader Dabit (Director of Developer Relations, Eigen Labs ), Branimir Rakic (Founder & CTO, OriginTrail ), Gustavo Massena (Co-Founder, Sunset Labs ), Erin Grasmick (Engineer, Parity ), Michael Bennallack (Founder, Mandala Chain ), Alex Mubert (Founder & CSO, Mubert ), Leemo (Chief Nice Officer, Nova Wallet ) and Simón Puebla (Head of BD, Crecimiento ).
Dozens more experts will participate in panels, talks and product launches, addressing a wide variety of topics such as DevRel, interoperability, capital markets, privacy, stablecoins, governance, gaming, music and artificial intelligence, while celebrating the technology, culture and collaborative spirit that drive the new era of decentralized systems.
With the aim of also attracting new audiences outside the ecosystem, the event will feature the participation of key figures from Uniswap, Dune, Arbitrum and EigenLabs.
“sub0 is not a passive conference; it’s about uniting communities from across Web3 to learn, connect, and build,” said Roman Kemper, founder of WebZero. “The lineup confirmed so far is already impressive, and we’ll be sharing more names soon.”
Over the next few weeks, new speakers will be announced, along with the full event agenda, which will offer a detailed look at everything attendees will be able to discover and experience at sub0 Symbiosis.
More information and an updated list of speakers or to apply to be a speaker: sub0.gg
Key event facts
About WebZero
WebZero is a global organization dedicated to events and the development of DevRel communities. It is responsible for presenting sub0 Symbiosis , the flagship conference of the Polkadot ecosystem, which will take place from November 14-16, 2025, in Buenos Aires, Argentina.
About Polkadot
Polkadot is the powerful and secure core of Web3, providing a shared foundation for uniting some of the world’s most transformative applications and blockchains.
It offers an advanced modular architecture that allows developers to easily design and build their own specialized blockchain projects, shared security that ensures high standards in block production across all connected chains, and a robust and transparent governance system where all participants have a voice in the evolution and sustainability of the ecosystem.